Arizona Cardinals vs San Francisco 49ers: every meeting, player stats and projections
At a glance
- Last meeting
- ARI 30, SF 36Sep 27, 2026 · Levi's Stadium, Santa Clara
- Record
- Cardinals 0–3 49ers in the last 3 meetings
- Next meeting
- 49ers at CardinalsSun, Jan 10, 12:00 AM ET
Game by game
| Date | Game | Score | Result | Stage |
|---|---|---|---|---|
| Jan 10, 2027 | 49ers at Cardinals | Not played yet | Scheduled | 2026 regular season, Week 18 |
| Sep 27, 2026 | Cardinals at 49ers | ARI 30, SF 36 | 49ers won | 2026 regular season, Week 3 |
| Nov 16, 2025 | 49ers at Cardinals | SF 41, ARI 22 | 49ers won | 2025 regular season, Week 11 |
| Sep 21, 2025 | Cardinals at 49ers | ARI 15, SF 16 | 49ers won | 2025 regular season, Week 3 |
Game leaders
Cardinals at 49ers, ARI 30, SF 36 · Sep 27, 2026
Arizona Cardinals- Passing
- Jacoby Brissett 38/52, 280 YDS, 2 TD
- Rushing
- Jeremiyah Love 21 CAR, 90 YDS
- Receiving
- Michael Wilson 11 REC, 89 YDS, 1 TD
San Francisco 49ers- Passing
- Brock Purdy 15/27, 297 YDS, 4 TD
- Rushing
- Christian McCaffrey 15 CAR, 75 YDS, 1 TD
- Receiving
- George Kittle 6 REC, 82 YDS, 2 TD
49ers at Cardinals, SF 41, ARI 22 · Nov 16, 2025
San Francisco 49ers- Passing
- Brock Purdy 19/26, 200 YDS, 3 TD
- Rushing
- Christian McCaffrey 13 CAR, 81 YDS, 2 TD
- Receiving
- George Kittle 6 REC, 67 YDS, 2 TD
Arizona Cardinals- Passing
- Jacoby Brissett 47/57, 452 YDS, 2 TD, 2 INT
- Rushing
- Bam Knight 5 CAR, 24 YDS, 1 TD
- Receiving
- Michael Wilson 15 REC, 185 YDS
Cardinals at 49ers, ARI 15, SF 16 · Sep 21, 2025
Arizona Cardinals- Passing
- Kyler Murray 22/35, 159 YDS, 1 TD
- Rushing
- Trey Benson 10 CAR, 42 YDS
- Receiving
- Marvin Harrison Jr. 3 REC, 44 YDS
San Francisco 49ers- Passing
- Mac Jones 27/41, 284 YDS, 1 TD, 1 INT
- Rushing
- Christian McCaffrey 17 CAR, 52 YDS
- Receiving
- Ricky Pearsall 8 REC, 117 YDS
Scores, schedule and game leaders via ESPN · updated Oct 21, 2026. Each name opens the player’s page.